Lymphoma, or cancer of the lymph glands is one of the most common types of cancers in Singapore. Diffuse large B-cell lymphoma (DLBCL) is a significant form of lymphoma. A diagnosis of lymphoma, especially Diffuse Large B-Cell Lymphoma (DLBCL), can be overwhelming. But for patients with lymphoma in Singapore, hope for a cure is real and growing.
With the emergence of newer targeted cancer therapies like Pola-R-CHP, bispecific antibodies and cellular gene therapies, lymphoma treatment in Singapore has become increasingly effective.
Advances in Lymphoma Treatment in Singapore: What Patients Should Know
Singapore has witnessed a transformative shift in treating aggressive lymphomas like DLBCL. According to Dr Lim Ziyi, Medical Director at CFCH, – we now have “better first-line treatment options for patients with more advanced DLBCL“.
One of the most recent breakthroughs is Pola-R-CHP. This targeted chemo-immunotherapy regimen has been proven to offer better progression-free survival (PFS) than the traditional R-CHOP regimen. For more than 20 years, R-CHOP was the gold standard for DLBCL. That changed with the introduction of Pola-R-CHP, which adds polatuzumab vedotin—a targeted antibody-drug conjugate—to the mix. Think of it like a smart bomb designed to find and destroy cancer cells while leaving healthy cells alone as much as possible. This new combination improves remission rates while keeping side effects manageable.
CFCH also stays at the forefront of innovative treatments, including immunotherapy options like CAR-T and bispecific antibodies for relapsed or refractory lymphoma cases. While patients in Singapore are fortunate to have access to these newer agents, other factors have to be considered before administering them. Logistics, such as the need for frequent visits or mode of administration and even cost, are important details to think about. As such, shared decision-making is crucial for each patient.
Personalised Cancer Care That Goes Beyond Treatment
CFCH is known for its personalised cancer care. Before starting any treatment, doctors do a full check-up, looking at the type and stage of non-Hodgkin lymphoma cancer and the patient’s overall health, including organ function, mental sharpness, nutrition, and support at home. This helps them create a treatment plan that is both effective and manageable.
Dr Joanne Lee, a haematologist at CFCH, focuses on making treatment more flexible. CFCH is offering options like shorter hospital stays, early discharges, and outpatient transplants. The goal is to administer safe lymphoma treatment while letting patients control their daily lives. With advances in digital health and AI, patients will soon be able to monitor parts of their treatment from home, too.
Dr Joanne Lee explains, “DLBCL isn’t one disease; it has many subtypes with distinct biology. Treatment options will differ. That’s why genetic testing and understanding a patient’s lifestyle and goals are essential.”
The Doctor-Patient Relationship: A Source of Strength
At CFCH, care goes beyond just medication and protocols. The emotional impact of a cancer diagnosis can be intense, and doctors like Dr Lee Chun Tsu focus on empathy, clarity, and building strong connections with patients. He believes that, “It’s not just about treating cancer—it’s about treating the whole person.”
Patients and their families are involved in every decision, from chemotherapy for lymphoma to supportive therapies. CFCH also supports the patient’s loved ones—spouses, parents, children, and close friends—recognising how vital they are in helping the patient cope and heal.
Catherine’s Story: Beating DLBCL with Support and Strength
Catherine, a young, fit, and healthy patient, faced her aggressive DLBCL diagnosis with “unwavering positivity”. She actively participated in her lymphoma treatment and remained steadfast through challenges like side effects and uncertainties, her determination inspiring Dr. Lee Chun Tsu.
By her side throughout her lymphoma journey was her husband, Jacky. He was a calm, steady presence through every scan, treatment and follow up. The support system for cancer patients often lies in the quiet strength of loved ones—offering comfort and courage that no medicine can replace.
For Catherine and many others at CFCH, the journey through DLBCL shows what resilience, advanced treatment, and compassionate care can achieve. As Dr Lee shares, “Now recovering from cancer for over 8 months and on the path to cure,” her story reflects the hope CFCH aims to bring to every patient.
Click here to read Catherine’s full story.
CFCH and Lymphoma Care in Singapore
At CFCH, lymphoma care is guided by a multidisciplinary team that brings together expertise from different medical specialities. By incorporating established global practices and focusing on whole-person care, the centre aims to support both effective treatment and patients’ overall quality of life. The approach goes beyond medical remission, with attention given to physical, emotional, and supportive aspects of recovery.
If you would like to learn more about personalised approaches to lymphoma treatment in Singapore, you can reach out to CFCH to discuss options for managing conditions such as DLBCL.
Frequently Asked Questions
1. How long does DLBCL treatment typically last in Singapore?
DLBCL treatment usually spans 4 to 6 months, depending on the regimen and individual response. Most patients receive chemotherapy every 3 weeks across several cycles, with regular scans to track progress.
2. Can DLBCL come back after remission?
Yes, DLBCL can relapse in some cases. However, newer therapies like Pola-R-CHP have improved long-term outcomes and reduced relapse risk. Regular follow-ups are key to early detection of recurrence.
3. What lifestyle changes can support recovery from DLBCL?
Maintaining a balanced diet, engaging in light physical activity (as advised), managing stress, and getting adequate sleep can support physical recovery and emotional well-being during and after treatment.
4. Are second opinions common for DLBCL patients in Singapore?
Absolutely. Many patients seek a second opinion before starting treatment, especially when evaluating options like genetic testing or newer therapies. Singapore’s healthcare system encourages informed, shared decision-making.
5. What are common chemotherapy side effects for lymphoma?
Standard chemotherapy side effects for lymphoma include fatigue, nausea, low white blood cell counts, and hair loss. These vary based on the regimen and patient health.
6. What does a cancer survivor journey typically involve?
A cancer survivor journey often includes physical recovery, emotional healing, and adjusting to life after treatment. Support systems and follow-up care are key to navigating this path.
7. Is there hope after lymphoma chemotherapy for lymphoma patients?
Yes, many patients experience remission and return to everyday life. Hope after lymphoma chemotherapy comes from advances in treatment and strong support systems.
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