Advancing Lymphoma Treatment in Singapore: Personalised Cancer Care at CFCH
Lymphoma, or cancer of the lymph glands is one of the most common types of cancers in Singapore. Diffuse large B-cell lymphoma (DLBCL) is a significant form of lymphoma. A diagnosis of lymphoma, especially Diffuse Large B-Cell Lymphoma (DLBCL), can be overwhelming. But for patients with lymphoma in Singapore, hope for a cure is real […]
DLBCL Journey of Catherine Choo: A story of Hope, Resilience, and Recovery from Lymphoma
Life was humming along beautifully for Catherine Choo. A successful professional and dedicated mother in her late 40s, she thrived at work and home. Her days were packed, but she loved the energy and purpose of juggling career and motherhood. That was until May 2024. From Breathlessness to Diagnosis: The Early Signs of DLBCL In […]
What is Smouldering Myeloma?
It is nearly impossible to explain smouldering multiple myeloma (SMM) without first talking about its neighbours on the disease spectrum: multiple myeloma and MGUS..
Gut Microbiome – The Role in Haematological Cancers and Impact on Response to Immunotherapy and Car-T Cell Therapy
The microbes in our gut, including bacteria, viruses, protozoa and fungi, exist in a state of ecological balance, influenced by various environmental factors such as geographical location, lifestyle choices, antibiotic use, and dietary habits. This delicate balance is known as the gut microbiome. It is estimated that there are over 40 trillion intestinal microorganisms, bringing […]
Navigating Through the Challenges of Living With Human Immunodeficiency Virus (HIV) and Lymphomas
T-cells, also known as T lymphocytes, are crucial to the immune system, which combats infection-causing pathogens (such as viruses, bacteria, fungi, and parasites) to eliminate harmful cells, like cancer cells. Human immunodeficiency virus (HIV) infection leads to a gradual decline in the function and number of a special type of T-cells called CD4+ helper T-cells […]
Older Patients With Relapsed Refractory Diffuse Large B cell Lymphoma Treated With Axi-cel Have Better Outcomes Compared With Chemoimmunotherapy
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, and patients with relapsed or refractory disease often have poor prognoses. This is particularly true for older adults, with comorbidities along with an increased risk for mortality and severe toxicity from intensive salvage chemoimmunotherapy (CIT) and may not be eligible for autologous […]
Treatment Options of Relapsed/Refractory Diffuse Large B cell Lymphoma (DLBCL)
“Relapsed” means the disease comes back after an improvement, while “refractory” means the lymphoma is not responding to treatment or the response is very short-lived. The majority (Up to 50-60%) of patients with Diffuse Large B cell lymphoma (DLBCL) can be potentially cured with standard chemoimmunotherapy, R-CHOP. 1 Even amongst patients who progress during initial […]
Immunotherapy in Blood Cancers
Cancer immunotherapy is a rapidly evolving field of oncology that harnesses the power of the immune system to recognise, attack, and eradicate cancer cells. While conventional cancer treatments such as chemotherapy and radiation therapy have improved outcomes for many patients, these approaches often have significant limitations. In contrast, immunotherapies have shown the potential to achieve […]
Acute Lymphoblastic Leukaemia: How Is It Different To Acute Myeloid Leukaemia?
When it comes to blood cancers, understanding the distinctions between different types is crucial for accurate diagnosis and effective treatment. While Acute Lymphoblastic Leukaemia (ALL) and Acute Myeloid Leukaemia (AML) may sound similar, there are differences between the two blood cancers. The primary difference between Acute Myeloid Leukaemia and Acute Lymphoblastic Leukaemia is the type […]
What To Expect After Being Diagnosed With AML
Receiving a diagnosis of Acute Myeloid Leukaemia (AML) can be a life-altering and overwhelming experience for both patients and their loved ones. We aim to provide you with valuable insights and information about the journey after an AML diagnosis. Understanding what to expect during this challenging time can help alleviate anxiety and empower you to […]